Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 10/20 | 0.49 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | GCGR | P47871 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28963643 | 0.98 | TLR8 (0.50) | TLR8NCEH1CNR1PARP1KDM4E | |
| SCHEMBL11235274 | 0.98 | TLR8 (0.50) | TLR8NCEH1CNR1PARP1KDM4E | |
| SCHEMBL9653105 | 0.98 | TLR8 (0.50) | TLR8NCEH1CNR1PARP1KDM4E | |
| SCHEMBL28965456 | 0.98 | TLR8 (0.50) | TLR8NCEH1CNR1PARP1KDM4E | |
| SCHEMBL9655141 | 0.98 | TLR8 (0.50) | TLR8NCEH1CNR1PARP1KDM4E | |
| SCHEMBL11129978 | 0.98 | TLR8 (0.50) | TLR8NCEH1CNR1PARP1KDM4E | |
| SCHEMBL28963639 | 0.98 | TLR8 (0.50) | TLR8NCEH1CNR1PARP1KDM4E | |
| SCHEMBL30287337 | 0.97 | TLR8 (0.49) | TLR8NCEH1CNR1PARP1KDM4E | |
| SCHEMBL30287379 | 0.97 | TLR8 (0.49) | TLR8NCEH1CNR1PARP1KDM4E | |
| SCHEMBL28633556 | 0.87 | ALDH1A1 (0.48) | TLR8NCEH1KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5082963-A | Water solubility | HOECHST CELANESE CORPORATION (US) | 1992-01-21 | — | — | US | disclosed |