SCHEMBL9724027

SCHEMBL9724027

CC(C)(C)Cc1cccc(C(=O)O)c1C(=O)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 3/20 0.49
POLB P06746 1/20 0.43
MYC P01106 1/20 0.41
CLCN2 P51788 1/20 0.41
ELANE P08246 1/20 0.41
TSHR P16473 1/20 0.41
FOLH1 Q04609 2/20 0.40
CDC25B P30305 1/20 0.40
ATM Q13315 1/20 0.40
ALDH1A1 P00352 2/20 0.39
ALOX15 P16050 2/20 0.39
NR4A1 P22736 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6906894 0.87 FOLH1 (0.44) AKR1C3CLCN2TSHRFOLH1ALDH1A1
SCHEMBL343948 0.85 FOLH1 (0.43) CLCN2TSHRFOLH1ALDH1A1ALOX15
SCHEMBL3953768 0.83 AKR1C3 (0.55) AKR1C3POLBMYCCLCN2TSHR
Benzoic Acid SCHEMBL11156159 0.82 TSHR (0.56) AKR1C3POLBCLCN2TSHRFOLH1
SCHEMBL5048768 0.81 FOLH1 (0.53) CLCN2TSHRFOLH1ALDH1A1ALOX15
SCHEMBL9498502 0.79 AKR1C3 (0.48) AKR1C3POLBFOLH1CDC25BATM
SCHEMBL10971044 0.78 AKR1C3 (0.52) AKR1C3POLBTSHRFOLH1CDC25B
SCHEMBL165213 0.77 AKR1C3 (0.71) AKR1C3POLBMYCTSHRCDC25B
SCHEMBL11654353 0.77 BID (0.52) AKR1C3CLCN2TSHRFOLH1ALOX15
SCHEMBL28863329 0.76 HMGB1 (0.38) CLCN2TSHRFOLH1ALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5107004-A 2-NEOPENTYLANTHRAQUINONE, PROCESSES FOR ITS PREPARATION AND METHODS FOR ITS USE BASF AKTIENGESELLSCHAFT (DE) 1992-04-21 US disclosed