Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.41 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BID | P55957 | 3/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.36 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.36 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6906894 | 0.98 | FOLH1 (0.44) | FOLH1ALOX15CLCN2HMGB1ALDH1A1 | |
| SCHEMBL28863329 | 0.87 | HMGB1 (0.38) | FOLH1ALOX15CLCN2HMGB1ALDH1A1 | |
| SCHEMBL9724027 | 0.85 | AKR1C3 (0.49) | FOLH1ALOX15CLCN2ALDH1A1TSHR | |
| SCHEMBL5048768 | 0.82 | FOLH1 (0.53) | FOLH1ALOX15CLCN2HMGB1ALDH1A1 | |
| SCHEMBL21651081 | 0.81 | BID (0.55) | ALOX15KDM4EHSD17B10BIDMCL1 | |
| SCHEMBL21771814 | 0.80 | BID (0.44) | ALOX15CLCN2KDM4EHSD17B10TSHR | |
| SCHEMBL123735 | 0.80 | CLCN2 (0.54) | FOLH1ALOX15CLCN2HMGB1ALDH1A1 | |
| SCHEMBL9498502 | 0.79 | AKR1C3 (0.48) | FOLH1ALOX15ALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL21651053 | 0.79 | RIPK1 (0.38) | FOLH1KDM4ERIPK1BIDMCL1 | |
| SCHEMBL10646485 | 0.79 | FOLH1 (0.43) | FOLH1ALOX15CLCN2HMGB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120016152-A1 | Process for the preparation of 4`-haloalkylbiphenyl-2-carboxylic acids | SALTIGO GMBH (DE) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016152-A1 | Process for the preparation of 4`-haloalkylbiphenyl-2-carboxylic acids | CYP4B1, HACL2, UGT1A4 | FOLH1 1070/4885ALOX15 1457/4885CLCN2 290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.