Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 15/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724187 | 0.91 | TYMS (0.75) | TYMS | |
| SCHEMBL9556405 | 0.85 | TYMS (1.00) | TYMS | |
| SCHEMBL9724196 | 0.83 | TYMS (0.73) | TYMS | |
| SCHEMBL10483296 | 0.82 | TYMS (0.59) | TYMS | |
| SCHEMBL9729742 | 0.82 | TYMS (0.74) | TYMS | |
| SCHEMBL9724174 | 0.82 | TYMS (0.75) | TYMS | |
| SCHEMBL9724271 | 0.82 | TYMS (0.75) | TYMS | |
| SCHEMBL9828890 | 0.79 | TYMS (0.88) | TYMS | |
| SCHEMBL9724140 | 0.77 | TYMS (0.68) | TYMS | |
| SCHEMBL9556260 | 0.76 | TYMS (1.00) | TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112837-A | Inhibitors of thymidylate synthetase enzyme | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-05-12 | — | — | US | disclosed |