Phthalic Acid

Phthalic Acid

SCHEMBL9724323

O=C(O)c1ccccc1C(=O)O.Oc1ccc(O)cc1

nearest known ligand 0.78

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.78
ALOX15 P16050 1/20 0.78
CA12 O43570 5/20 0.64
CA1 P00915 5/20 0.64
CA2 P00918 5/20 0.64
CA9 Q16790 5/20 0.64
CA14 Q9ULX7 5/20 0.64
CA7 P43166 4/20 0.64
CA4 P22748 3/20 0.64
CA6 P23280 2/20 0.64
KDM4E B2RXH2 1/20 0.64
HMGB1 P09429 1/20 0.64
HPGD P15428 1/20 0.64
SMN1; SMN2 Q16637 1/20 0.64
NAPRT Q6XQN6 1/20 0.64
TDP1 Q9NUW8 3/20 0.61
GAA P10253 1/20 0.61
KMT2A Q03164 1/20 0.61
IDE P14735 1/20 0.59
AKR1C3 P42330 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL251478 0.94 ALDH1A1 (0.78) ALDH1A1ALOX15CA12CA1CA2
Phthalic Acid SCHEMBL1779427 0.94 ALDH1A1 (0.78) ALDH1A1ALOX15CA12CA1CA2
Phthalic Acid SCHEMBL29523381 0.94 ALDH1A1 (0.78) ALDH1A1ALOX15CA12CA1CA2
Phthalic Acid SCHEMBL18438875 0.92 ALDH1A1 (0.74) ALDH1A1ALOX15CA12CA1CA2
Phthalic Acid SCHEMBL27771539 0.92 ALDH1A1 (0.74) ALDH1A1ALOX15CA12CA1CA2
Phthalic Acid SCHEMBL146125 0.88 ALDH1A1 (1.00) ALDH1A1ALOX15CA12CA1CA2
Phthalic Acid SCHEMBL5668586 0.88 ALDH1A1 (1.00) ALDH1A1ALOX15CA12CA1CA2
Phthalic Acid SCHEMBL1686043 0.88 ALDH1A1 (1.00) ALDH1A1ALOX15CA12CA1CA2
Phthalic Acid SCHEMBL4452470 0.88 ALDH1A1 (1.00) ALDH1A1ALOX15CA12CA1CA2
Phthalic Acid SCHEMBL10477086 0.88 ALDH1A1 (1.00) ALDH1A1ALOX15CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5166208-A Antitumor agents; antibiotics BOSTON COLLEGE (US) 1992-11-24 US disclosed