Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 8/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9374182 | 0.80 | AR (0.41) | NPSR1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL9724434 | 0.76 | NPSR1 (0.55) | NPSR1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL3380584 | 0.75 | KMT2A (0.52) | NPSR1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL21037002 | 0.73 | MEN1 (0.37) | NPSR1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL3378905 | 0.69 | KMT2A (0.49) | NPSR1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL12239455 | 0.67 | ALDH1A1 (0.61) | NPSR1KMT2AMEN1CYP2A6ALDH1A1 | |
| SCHEMBL8185276 | 0.65 | CYP2A6 (0.46) | KMT2AMEN1CYP2A6SMN1; SMN2LMNA | |
| SCHEMBL28981619 | 0.65 | CYP2A6 (0.94) | CYP2A6SMN1; SMN2ALDH1A1ALDH1A3KDM4E | |
| SCHEMBL7038721 | 0.64 | ALDH1A1 (0.61) | KMT2AMEN1CYP2A6SMN1; SMN2GAA | |
| SCHEMBL16357246 | 0.63 | P2RX4 (0.43) | NPSR1KMT2AMEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5137795-A | Photosensitivity, contrast | AGFA-GEVAERT, N.V. (BE) | 1992-08-11 | — | — | US | disclosed |
| EP-0452569-A1 | Electrophotographic recording material | AGFA-GEVAERT N.V. (BE) | 1991-10-23 | — | — | EP | disclosed |