Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.64 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.54 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7276961 | 1.00 | ACE (0.64) | ACENOTUMHSD17B3TSHR | |
| SCHEMBL28162113 | 0.84 | ACE (0.60) | ACE | |
| SCHEMBL30745240 | 0.84 | NOTUM (0.66) | ACENOTUM | |
| SCHEMBL2824809 | 0.84 | NOTUM (0.66) | ACENOTUM | |
| SCHEMBL29697839 | 0.84 | NOTUM (0.66) | ACENOTUM | |
| SCHEMBL2830596 | 0.84 | NOTUM (0.66) | ACENOTUM | |
| SCHEMBL31207052 | 0.84 | NOTUM (0.66) | ACENOTUM | |
| SCHEMBL2824813 | 0.84 | NOTUM (0.66) | ACENOTUM | |
| SCHEMBL2827480 | 0.83 | NOTUM (0.64) | ACENOTUM | |
| SCHEMBL2827489 | 0.83 | NOTUM (0.64) | ACENOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5157041-A | Viricides | HOFFMANN-LA ROCHE INC. (US) | 1992-10-20 | — | — | US | disclosed |