Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 9/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.57 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL970254 | 1.00 | APP (0.60) | APPALDH1A1MEN1USP2LMNA | |
| SCHEMBL14174231 | 0.90 | APP (0.60) | APPALDH1A1MEN1USP2LMNA | |
| SCHEMBL18429761 | 0.90 | APP (0.77) | APPALDH1A1MEN1USP2LMNA | |
| SCHEMBL50816 | 0.89 | APP (0.65) | APPALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL3085759 | 0.89 | APP (0.67) | APPALDH1A1MEN1USP2LMNA | |
| SCHEMBL24303208 | 0.89 | APP (0.67) | APPALDH1A1MEN1USP2LMNA | |
| SCHEMBL12703442 | 0.88 | APP (0.57) | APPALDH1A1MEN1USP2LMNA | |
| SCHEMBL466232 | 0.87 | APP (0.65) | APPALDH1A1MEN1USP2LMNA | |
| SCHEMBL77535 | 0.87 | ALDH1A1 (0.60) | APPALDH1A1LMNACYP3A4SMN1; SMN2 | |
| SCHEMBL14173685 | 0.84 | APP (0.55) | APPALDH1A1MEN1USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2259137-B1 | METHOD FOR PRODUCING A OF LITHOGRAPHIC PRINTING PLATE | FUJIFILM CORP (JP) | 2016-08-31 | — | — | EP | disclosed |
| US-20110168044-A1 | METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE | FUJIFILM CORPORATION (JP) | 2011-07-14 | — | — | US | disclosed |
| EP-2330464-A1 | PROCESS FOR PRODUCING LITHOGRAPHIC PRINTING PLATE | FUJIFILM Corporation (JP) | 2011-06-08 | — | — | EP | disclosed |
| US-7943637-B2 | Thienopyridine derivatives and the use thereof as HSP90 modulators | MERCK PATENT GMBH (DE) | 2011-05-17 | — | — | US | disclosed |
| US-7943637-B2 | Thienopyridine derivatives and the use thereof as HSP90 modulators | MERCK PATENT GMBH (DE) | 2011-05-17 | — | — | US | disclosed |
| US-20110020751-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PRODUCTION PROCESS OF LITHOGRAPHIC PRINTING PLATE USING THE PRECURSOR | FUJIFILM CORPORATION (JP) | 2011-01-27 | — | — | US | disclosed |
| EP-2259137-A1 | ORIGINAL PLATE FOR LITHOGRAPHIC PRINTING PLATE, AND METHOD FOR PRODUCTION OF LITHOGRAPHIC PRINTING PLATE USING THE SAME | FUJIFILM Corporation (JP) | 2010-12-08 | — | — | EP | disclosed |
| US-20090054452-A1 | Thienopyridine Derivatives and the Use Thereof as Hsp90 Modulators | MERCK PATENT GMBH (DE) | 2009-02-26 | — | — | US | disclosed |
| US-20090054452-A1 | Thienopyridine Derivatives and the Use Thereof as Hsp90 Modulators | MERCK PATENT GMBH (DE) | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054452-A1 | Thienopyridine Derivatives and the Use Thereof as Hsp90 Modulators | HSP90AA1, HSP90AB1, HSP90AB2P | APP 2804/4885ALDH1A1 1033/4885MEN1 4561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.