Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9386771 | 1.00 | ESR1 (0.35) | ESR1CHRM1SLC6A4KCNH2SLC29A1 | |
| SCHEMBL9383921 | 1.00 | ESR1 (0.35) | ESR1CHRM1SLC6A4KCNH2SLC29A1 | |
| SCHEMBL9386828 | 0.94 | FAAH (0.33) | ESR1CHRM1SLC6A4KCNH2SLC29A1 | |
| SCHEMBL9385045 | 0.89 | FAAH (0.33) | ESR1CHRM1SLC6A4KCNH2SLC29A1 | |
| SCHEMBL9387188 | 0.89 | FAAH (0.33) | ESR1CHRM1SLC6A4KCNH2SLC29A1 | |
| SCHEMBL9386415 | 0.88 | FAAH (0.33) | ESR1CHRM1SLC6A4KCNH2SLC29A1 | |
| SCHEMBL9194073 | 0.86 | ESR1 (0.39) | ESR1CHRM1SLC6A4KCNH2SLC29A1 | |
| SCHEMBL9697860 | 0.86 | ESR1 (0.34) | ESR1CHRM1SLC6A4KCNH2SLC29A1 | |
| SCHEMBL9384446 | 0.86 | ESR1 (0.46) | ESR1CHRM1SLC6A4KCNH2SLC29A1 | |
| SCHEMBL9386632 | 0.86 | ESR1 (0.46) | ESR1CHRM1SLC6A4KCNH2SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102877-A | Carbapenicillin antibiotics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |
| EP-0394991-A1 | 1-Azabicyclo(3.2.0)Hept-2-Ene-2-carboxylic acid compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-31 | — | — | EP | disclosed |