Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | FASN | P49327 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 6/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724735 | 1.00 | ALDH1A1 (0.61) | ALDH1A1TSHRFASNFAAHTRPV1 | |
| SCHEMBL18398895 | 0.98 | ALDH1A1 (0.59) | ALDH1A1TSHRFASNFAAHTRPV1 | |
| SCHEMBL1237969 | 0.98 | ALDH1A1 (0.59) | ALDH1A1TSHRFASNFAAHTRPV1 | |
| SCHEMBL7289157 | 0.98 | ALDH1A1 (0.59) | ALDH1A1TSHRFASNFAAHTRPV1 | |
| SCHEMBL19063519 | 0.98 | ALDH1A1 (0.59) | ALDH1A1TSHRFASNFAAHTRPV1 | |
| SCHEMBL17479081 | 0.98 | ALDH1A1 (0.59) | ALDH1A1TSHRFASNFAAHTRPV1 | |
| SCHEMBL1239783 | 0.98 | ALDH1A1 (0.59) | ALDH1A1TSHRFASNFAAHTRPV1 | |
| SCHEMBL3130547 | 0.98 | ALDH1A1 (0.59) | ALDH1A1TSHRFASNFAAHTRPV1 | |
| SCHEMBL11030145 | 0.98 | ALDH1A1 (0.59) | ALDH1A1TSHRFASNFAAHTRPV1 | |
| SCHEMBL18398897 | 0.98 | ALDH1A1 (0.59) | ALDH1A1TSHRFASNFAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3027754-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | enEvolv, Inc. (US) | 2016-06-08 | — | — | EP | disclosed |
| WO-2015017866-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. (US) | 2015-02-05 | — | — | WO | disclosed |
| US-5096884-A | Antitumor agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1992-03-17 | — | — | US | disclosed |
| EP-0437244-A1 | Glidobactin PF-1 peptide antitumor antibiotics | Bristol-Myers Squibb Company (US) | 1991-07-17 | — | — | EP | disclosed |