⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3677847 | 0.69 | — | — | |
| SCHEMBL7103345 | 0.69 | — | — | |
| SCHEMBL18868903 | 0.64 | — | — | |
| SCHEMBL11823263 | 0.64 | CYP1A2 (0.50) | — | |
| SCHEMBL20409388 | 0.59 | — | — | |
| SCHEMBL11189067 | 0.59 | — | — | |
| SCHEMBL12571300 | 0.58 | TSHR (0.59) | — | |
| SCHEMBL2003065 | 0.53 | — | — | |
| SCHEMBL14891491 | 0.53 | — | — | |
| SCHEMBL8878345 | 0.52 | FBP1 (0.70) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4835168-A | Thiadiazole antiviral agents | ELI LILLY AND COMPANY (US) | 1989-05-30 | — | — | US | claimed |
| US-5093324-A | Ribose-substituted | ELI LILLY AND COMPANY (US) | 1992-03-03 | — | — | US | disclosed |
| CN-1014242-B | PREPN. OF THIADIAZOLE COMPOUNDS | LILLY CO ELI (US) | 1991-10-09 | — | — | CN | disclosed |
| EP-0229501-B1 | THIADIAZOLE ANTIVIRAL AGENTS | ELI LILLY AND COMPANY (US) | 1990-12-27 | — | — | EP | disclosed |
| EP-0392769-A1 | Thiadiazole antiviral agents | ELI LILLY AND COMPANY (US) | 1990-10-17 | — | — | EP | disclosed |
| US-4835168-A | Thiadiazole antiviral agents | ELI LILLY AND COMPANY (US) | 1989-05-30 | — | — | US | disclosed |
| CN-86108507-A | The thiadiazole antiviral agent | — | 1987-08-05 | — | — | CN | disclosed |
| EP-0229501-A1 | Thiadiazole antiviral agents | ELI LILLY AND COMPANY (US) | 1987-07-22 | — | — | EP | disclosed |