Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.49 |
| ▸ | RET | P07949 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | RARB | P10826 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8727134 | 0.95 | KMT2A (0.61) | KMT2ASMN1; SMN2MAPTTP53HSD17B10 | |
| SCHEMBL18087016 | 0.94 | KMT2A (0.62) | KMT2ASMN1; SMN2MAPTHSD17B10MEN1 | |
| SCHEMBL18087026 | 0.92 | KMT2A (0.60) | KMT2ASMN1; SMN2MAPTTP53HSD17B10 | |
| SCHEMBL7500294 | 0.89 | KMT2A (0.58) | KMT2ASMN1; SMN2MAPTTP53HSD17B10 | |
| SCHEMBL5696715 | 0.88 | KMT2A (0.68) | KMT2ASMN1; SMN2MAPTHSD17B10MEN1 | |
| SCHEMBL13557797 | 0.88 | KMT2A (0.62) | KMT2ASMN1; SMN2MAPTHSD17B10MEN1 | |
| SCHEMBL18381106 | 0.88 | KMT2A (0.62) | KMT2ASMN1; SMN2MAPTHSD17B10MEN1 | |
| SCHEMBL5696854 | 0.88 | KMT2A (0.68) | KMT2ASMN1; SMN2MAPTHSD17B10MEN1 | |
| SCHEMBL15549028 | 0.88 | KMT2A (0.68) | KMT2ASMN1; SMN2MAPTHSD17B10MEN1 | |
| SCHEMBL38661498 | 0.88 | KMT2A (0.68) | KMT2ASMN1; SMN2MAPTHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5100579-A | POLYPHENYL-BASED ESTER COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS CONTAINING SAME | AJINOMOTO CO., INC. (JP) | 1992-03-31 | — | — | US | disclosed |
| EP-0191600-B1 | POLYPHENYL-BASED ESTER COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS CONTAINING SAME | AJINOMOTO CO., INC. (JP) | 1991-12-27 | — | — | EP | disclosed |
| US-4911861-A | Mixture of at least two components | AJINOMOTO CO., INC. (JP) | 1990-03-27 | — | — | US | disclosed |
| US-4728458-A | FERROELECTRIC | AJINOMOTO CO., LTD. (JP) | 1988-03-01 | — | — | US | disclosed |
| EP-0191600-A2 | Polyphenyl-based ester compounds and liquid crystal compositions containing same | AJINOMOTO CO., INC. (JP) | 1986-08-20 | — | — | EP | disclosed |