Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.61 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.60 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.59 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.59 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.59 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.59 |
| ▸ | CTSV | O60911 | 1/20 | 0.57 |
| ▸ | CTSL | P07711 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.56 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23283414 | 0.87 | LTA4H (0.62) | LTA4HNR1H4PDK1PDK2PDK3 | |
| SCHEMBL1142086 | 0.86 | LTA4H (0.64) | LTA4HNR1H4PDK1PDK2PDK3 | |
| SCHEMBL7933622 | 0.86 | LTA4H (0.61) | LTA4HNR1H4PDK1PDK2PDK3 | |
| SCHEMBL5249717 | 0.85 | NR1H4 (0.65) | LTA4HNR1H4PDK1PDK2PDK3 | |
| SCHEMBL11681284 | 0.85 | LTA4H (0.63) | LTA4HNR1H4PDK1PDK2PDK3 | |
| SCHEMBL28390021 | 0.84 | MEN1 (0.71) | LTA4HNR1H4PDK1PDK2PDK3 | |
| SCHEMBL832694 | 0.84 | LTA4H (0.65) | LTA4HNR1H4PDK1PDK2PDK3 | |
| SCHEMBL23273969 | 0.84 | LTA4H (0.65) | LTA4HPDK1PDK2PDK3PDK4 | |
| SCHEMBL10599853 | 0.83 | MEN1 (0.79) | LTA4HNR1H4PDK1PDK2PDK3 | |
| SCHEMBL8119011 | 0.83 | SIRT2 (0.64) | LTA4HNR1H4PDK1PDK2PDK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098934-A | Enkephalinase inhibitors as analgesics or anticargcinogenic agents | ROUSSEL UCLAF (FR) | 1992-03-24 | — | — | US | disclosed |