Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | NAAA | Q02083 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | MLYCD | O95822 | 1/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27907061 | 0.94 | L3MBTL1 (0.65) | SMN1; SMN2L3MBTL1NAAATRPV1CA2 | |
| SCHEMBL3626979 | 0.94 | L3MBTL1 (0.65) | SMN1; SMN2L3MBTL1NAAATRPV1CA2 | |
| SCHEMBL9725132 | 0.94 | L3MBTL1 (0.65) | SMN1; SMN2L3MBTL1NAAATRPV1CA2 | |
| SCHEMBL9142025 | 0.94 | L3MBTL1 (0.65) | SMN1; SMN2L3MBTL1NAAATRPV1CA2 | |
| SCHEMBL10029414 | 0.90 | L3MBTL1 (0.58) | SMN1; SMN2L3MBTL1HDAC6CA2XDH | |
| SCHEMBL24440484 | 0.90 | HDAC6 (0.60) | SMN1; SMN2L3MBTL1HDAC6CA2XDH | |
| SCHEMBL29633482 | 0.90 | HDAC6 (0.60) | SMN1; SMN2L3MBTL1HDAC6CA2XDH | |
| SCHEMBL18619400 | 0.88 | HDAC6 (0.58) | SMN1; SMN2L3MBTL1NAAAHDAC6XDH | |
| SCHEMBL28051808 | 0.86 | SMN1; SMN2 (0.62) | SMN1; SMN2L3MBTL1NAAATSHRHTT | |
| SCHEMBL15985355 | 0.85 | HDAC6 (0.51) | SMN1; SMN2HDAC6CA2XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5140020-A | Antiinflammatory agents | KUREHA KAGATU KOGYO KABUSHIKI KAISHA (JP) | 1992-08-18 | — | — | US | claimed |
| EP-0142241-B1 | DIHYDROXYBENZAMIDE DERIVATIVES HAVING ANTI-INFLAMMATORY ACTIVITY | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1987-12-02 | — | — | EP | claimed |
| EP-0142241-A1 | Dihydroxybenzamide derivatives having anti-inflammatory activity | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-05-22 | — | — | EP | claimed |
| EP-0142241-A1 | Dihydroxybenzamide derivatives having anti-inflammatory activity | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-05-22 | — | — | EP | disclosed |