Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CTSG | P08311 | 1/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14533743 | 0.80 | CSNK1E (0.40) | CSNK1EKCNH2HTR2APRSS1PRSS2 | |
| SCHEMBL28724613 | 0.80 | MEN1 (0.45) | CSNK1EPRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL11177019 | 0.80 | CSNK1E (0.41) | CSNK1EKCNH2HTR2APRSS1ALDH1A1 | |
| SCHEMBL29780652 | 0.79 | CSNK1E (0.44) | CSNK1EKCNH2HTR2APRSS1PRSS2 | |
| SCHEMBL29160983 | 0.79 | CSNK1E (0.44) | CSNK1EKCNH2HTR2APRSS1PRSS2 | |
| SCHEMBL28515832 | 0.78 | PRSS1 (0.40) | CSNK1EPRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL14533922 | 0.78 | CSNK1E (0.35) | CSNK1EHTR2APRSS1PRSS2PRSS3 | |
| Phosphine SCHEMBL28856691 | 0.76 | MEN1 (0.41) | CSNK1EKCNH2HTR2AMEN1KMT2A | |
| Phosphine SCHEMBL2673731 | 0.76 | MEN1 (0.41) | CSNK1EKCNH2HTR2AMEN1KMT2A | |
| Phosphine SCHEMBL10797446 | 0.76 | MEN1 (0.41) | CSNK1EKCNH2HTR2AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166205-A | DERIVATIVES OF 1-DIPHENYLMETHYL PIPERAZINE AND THEIR USE AS ANTIHISTAMINES | LABORATORIOS DEL DR. ESTEVE, S. A. (ES) | 1992-11-24 | — | — | US | disclosed |