Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.44 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.44 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.44 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28775024 | 0.89 | HTT (0.56) | HTTFGFR1POLBALDH1A1TUBB4A | |
| SCHEMBL27238830 | 0.84 | HTT (0.47) | HTTFGFR1POLBALDH1A1TUBB4A | |
| SCHEMBL30846080 | 0.84 | HTT (0.47) | HTTFGFR1POLBALDH1A1TUBB4A | |
| SCHEMBL23266636 | 0.79 | HTT (0.60) | HTTFGFR1POLBALDH1A1 | |
| SCHEMBL366895 | 0.78 | HTT (0.47) | HTTFGFR1POLBALDH1A1TUBB4A | |
| SCHEMBL9725331 | 0.77 | HTT (0.46) | HTTFGFR1POLBALDH1A1MEN1 | |
| SCHEMBL3417306 | 0.77 | HTT (0.73) | HTTFGFR1POLBALDH1A1 | |
| SCHEMBL5937 | 0.76 | HTT (0.56) | HTTFGFR1POLBALDH1A1NPC1 | |
| SCHEMBL3496264 | 0.76 | HTT (0.72) | HTTFGFR1ALDH1A1KMT2AMAPT | |
| SCHEMBL29898298 | 0.76 | HTT (0.56) | HTTFGFR1POLBALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081256-A | Para ordered aromatic diacids containing benzimidazole groups | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1992-01-14 | — | — | US | disclosed |
| US-5081256-A | Para ordered aromatic diacids containing benzimidazole groups | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1992-01-14 | — | — | US | disclosed |