Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18083455 | 0.90 | HTT (0.51) | HTTPOLBFGFR1ALDH1A1IKBKE | |
| SCHEMBL4952690 | 0.90 | HTT (0.40) | HTTPOLBFGFR1ALDH1A1IKBKE | |
| SCHEMBL20879851 | 0.80 | POLB (0.43) | HTTPOLBALDH1A1IKBKE | |
| SCHEMBL16147684 | 0.79 | CYP11B1 (0.41) | HTTPOLBFGFR1ALDH1A1IKBKE | |
| SCHEMBL2039920 | 0.78 | HTT (0.66) | HTTFGFR1ALDH1A1MAPTKDM4E | |
| SCHEMBL8188627 | 0.78 | FGFR1 (0.61) | HTTFGFR1GABRPGABRDGABRA1 | |
| SCHEMBL9725330 | 0.77 | HTT (0.50) | HTTPOLBFGFR1ALDH1A1MAPT | |
| SCHEMBL23266636 | 0.76 | HTT (0.60) | HTTPOLBFGFR1ALDH1A1 | |
| SCHEMBL840022 | 0.75 | HTT (0.51) | HTTPOLBFGFR1ALDH1A1IKBKE | |
| SCHEMBL10552778 | 0.75 | POLB (0.55) | HTTPOLBFGFR1ALDH1A1IKBKE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081256-A | Para ordered aromatic diacids containing benzimidazole groups | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1992-01-14 | — | — | US | disclosed |