Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KCNQ2 | O43526 | 4/20 | 0.43 |
| ▸ | KCNQ4 | P56696 | 4/20 | 0.43 |
| ▸ | KCNQ3 | O43525 | 3/20 | 0.43 |
| ▸ | KCNQ5 | Q9NR82 | 3/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9725391 | 0.89 | CYP1A2 (0.56) | CYP1A2CYP2C9CYP2C19SMN1; SMN2KCNQ2 | |
| SCHEMBL9725489 | 0.86 | CYP1A2 (0.46) | CYP1A2CYP2C9CYP2C19SMN1; SMN2MAPT | |
| SCHEMBL9725494 | 0.86 | CYP1A2 (0.46) | CYP1A2CYP2C9CYP2C19SMN1; SMN2MAPT | |
| SCHEMBL9827552 | 0.85 | ALDH1A1 (0.47) | CYP1A2CYP2C9CYP2C19SMN1; SMN2KCNQ2 | |
| SCHEMBL9725414 | 0.83 | ALDH1A1 (0.49) | CYP1A2CYP2C9CYP2C19SMN1; SMN2HTR1A | |
| SCHEMBL9725485 | 0.82 | CYP1A2 (0.56) | CYP1A2CYP2C9CYP2C19SMN1; SMN2HSD17B10 | |
| SCHEMBL9725378 | 0.80 | DPP4 (0.42) | CYP1A2CYP2C9CYP2C19SMN1; SMN2HSD17B10 | |
| SCHEMBL9725365 | 0.79 | CYP1A2 (0.43) | CYP1A2CYP2C9CYP2C19SMN1; SMN2MAPT | |
| SCHEMBL9725425 | 0.78 | ALDH1A1 (0.44) | CYP1A2CYP2C9CYP2C19SMN1; SMN2KCNQ2 | |
| SCHEMBL9175285 | 0.74 | CYP1A2 (0.61) | CYP1A2CYP2C9CYP2C19SMN1; SMN2KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162318-A | Which have pulmonary surfactant secretion promoting activity | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0454330-A1 | Benzimidazolinone derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-10-30 | — | — | EP | disclosed |