Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.77 |
| ▸ | HPGD | P15428 | 2/20 | 0.77 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.64 |
| ▸ | CES1 | P23141 | 3/20 | 0.63 |
| ▸ | CES2 | O00748 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butyrophenone SCHEMBL25423577 | 1.00 | L3MBTL1 (0.77) | L3MBTL1SMN1; SMN2HPGDHSD17B3MAPT | |
| Butyrophenone SCHEMBL82532 | 1.00 | L3MBTL1 (0.77) | L3MBTL1SMN1; SMN2HPGDHSD17B3MAPT | |
| Butyrophenone SCHEMBL11522791 | 1.00 | L3MBTL1 (0.77) | L3MBTL1SMN1; SMN2HPGDHSD17B3MAPT | |
| Butyrophenone SCHEMBL27921458 | 0.98 | L3MBTL1 (0.74) | L3MBTL1SMN1; SMN2HPGDHSD17B3MAPT | |
| Butyrophenone SCHEMBL11310788 | 0.98 | L3MBTL1 (0.74) | L3MBTL1SMN1; SMN2HPGDHSD17B3MAPT | |
| Butyrophenone SCHEMBL28260771 | 0.98 | L3MBTL1 (0.74) | L3MBTL1SMN1; SMN2HPGDHSD17B3MAPT | |
| Butyrophenone SCHEMBL7218951 | 0.98 | L3MBTL1 (0.74) | L3MBTL1SMN1; SMN2HPGDHSD17B3MAPT | |
| Butyrophenone SCHEMBL28311799 | 0.96 | L3MBTL1 (0.71) | L3MBTL1SMN1; SMN2HPGDHSD17B3MAPT | |
| Butyrophenone SCHEMBL6307349 | 0.96 | L3MBTL1 (0.71) | L3MBTL1SMN1; SMN2HPGDHSD17B3MAPT | |
| Butyrophenone SCHEMBL28047674 | 0.96 | L3MBTL1 (0.71) | L3MBTL1SMN1; SMN2HPGDHSD17B3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162318-A | Which have pulmonary surfactant secretion promoting activity | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0454330-A1 | Benzimidazolinone derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-10-30 | — | — | EP | disclosed |
| US-4987132-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| EP-0279681-A2 | Saturated heterocyclic carboxamide derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |