Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 2/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 3/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4608729 | 0.98 | LMNA (0.35) | LMNASMN1; SMN2ESR2ALDH1A1HSP90AA1 | |
| SCHEMBL2477501 | 0.86 | CA1 (0.38) | SMN1; SMN2CA1CA9MAOAMAOB | |
| SCHEMBL28411162 | 0.80 | KMT2A (0.32) | MEN1KMT2A | |
| SCHEMBL14967792 | 0.80 | ESR1 (0.38) | LMNASMN1; SMN2ESR2ALDH1A1HSP90AA1 | |
| SCHEMBL597282 | 0.80 | CA1 (0.40) | LMNAALDH1A1HSP90AA1HSP90AB1TP53 | |
| SCHEMBL4157033 | 0.80 | CA1 (0.40) | LMNAALDH1A1HSP90AA1HSP90AB1TP53 | |
| SCHEMBL197445 | 0.80 | CA1 (0.40) | LMNAALDH1A1HSP90AA1HSP90AB1TP53 | |
| SCHEMBL3174046 | 0.80 | CA1 (0.40) | LMNAALDH1A1HSP90AA1HSP90AB1TP53 | |
| SCHEMBL2483184 | 0.80 | CA1 (0.40) | LMNAALDH1A1HSP90AA1HSP90AB1TP53 | |
| SCHEMBL28580296 | 0.80 | CA1 (0.40) | LMNAALDH1A1HSP90AA1HSP90AB1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124224-A | Toner compositions and processes with polyethylenes including a linear crystalline polyethylene | XEROX CORPORATION (US) | 1992-06-23 | — | — | US | claimed |
| US-5124224-A | Toner compositions and processes with polyethylenes including a linear crystalline polyethylene | XEROX CORPORATION (US) | 1992-06-23 | — | — | US | disclosed |