Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | PAM | P19021 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL727278 | 0.78 | IDO1 (0.48) | MAOBIDO1PAML3MBTL1NPC1 | |
| SCHEMBL2142092 | 0.78 | ALDH1A1 (0.56) | ALDH1A1CYP2A6MAOBTSHRIDO1 | |
| SCHEMBL7736539 | 0.77 | IDO1 (0.52) | ALDH1A1CYP2A6MAOBIDO1PAM | |
| SCHEMBL7736535 | 0.77 | IDO1 (0.52) | ALDH1A1CYP2A6MAOBIDO1PAM | |
| SCHEMBL3035504 | 0.75 | ALDH1A1 (0.42) | ALDH1A1CYP2A6MAOBTSHRIDO1 | |
| SCHEMBL6158360 | 0.75 | ALDH1A1 (0.42) | ALDH1A1CYP2A6MAOBTSHRIDO1 | |
| SCHEMBL6158362 | 0.75 | ALDH1A1 (0.42) | ALDH1A1CYP2A6MAOBTSHRIDO1 | |
| SCHEMBL9491843 | 0.73 | ALDH1A1 (0.40) | ALDH1A1CYP2A6MAOBTSHRIDO1 | |
| SCHEMBL9784248 | 0.73 | ALDH1A1 (0.40) | ALDH1A1CYP2A6MAOBTSHRIDO1 | |
| SCHEMBL3031384 | 0.73 | ALDH1A1 (0.40) | ALDH1A1CYP2A6MAOBTSHRIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171356-A | Thiolcarbamate and nonphytotoxic extender which minimizes soil degradation | ICI AMERICAS INC. (US) | 1992-12-15 | — | — | US | disclosed |