SCHEMBL9725638

SCHEMBL9725638

CCOC(=O)N(CC=CCl)CC=CCl

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.36
LMNA P02545 1/20 0.34
HSD17B10 Q99714 1/20 0.34
ALOX15 P16050 1/20 0.33
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
SOAT1 P35610 1/20 0.33
HCAR2 Q8TDS4 1/20 0.32
CTDSP1 Q9GZU7 1/20 0.32
NPSR1 Q6W5P4 1/20 0.31
GLO1 Q04760 1/20 0.31
TRPA1 O75762 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 2/20 0.30
MEN1 O00255 1/20 0.30
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9473687 0.93 MAPT (0.34) ALDH1A1LMNAHSD17B10MAPT
SCHEMBL9473689 0.93 MAPT (0.34) ALDH1A1LMNAHSD17B10MAPT
SCHEMBL10393358 0.82 ALDH1A1 (0.34) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL9725736 0.79
SCHEMBL9725617 0.78
SCHEMBL9725696 0.77 CYP3A4 (0.34) ALDH1A1HSD17B10MAPTKMT2AMEN1
SCHEMBL9725635 0.76 CA12 (0.33)
SCHEMBL8741050 0.76 MAPT (0.35) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL9725596 0.76 NPC1 (0.33)
SCHEMBL8741051 0.76 MAPT (0.35) ALDH1A1LMNAHSD17B10ALOX15MGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5171356-A Thiolcarbamate and nonphytotoxic extender which minimizes soil degradation ICI AMERICAS INC. (US) 1992-12-15 US disclosed
EP-0175332-B1 HERBICIDE COMPOSITIONS OF EXTENDED SOIL LIFE STAUFFER CHEMICAL COMPANY (US) 1992-03-18 EP disclosed