Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butylate SCHEMBL9236447 | 0.82 | TSHR (0.38) | TSHRMAPK1L3MBTL1MEN1KMT2A | |
| Vernolate SCHEMBL9331760 | 0.79 | TSHR (0.53) | TSHRMAPK1L3MBTL1MEN1KMT2A | |
| S-Ethyl Dipropylcarbamothioate SCHEMBL66482 | 0.78 | TSHR (1.00) | TSHRMAPK1MEN1KMT2ATDP1 | |
| S-Ethyl Dipropylcarbamothioate SCHEMBL8541416 | 0.78 | TSHR (1.00) | TSHRMAPK1MEN1KMT2ATDP1 | |
| Molinate SCHEMBL9464047 | 0.77 | L3MBTL1 (0.38) | L3MBTL1MEN1KMT2ATDP1HTT | |
| S-Ethyl Dipropylcarbamothioate SCHEMBL10793164 | 0.77 | TSHR (0.80) | TSHRMAPK1MEN1KMT2ANPSR1 | |
| S-Ethyl Dipropylcarbamothioate SCHEMBL8074575 | 0.77 | TSHR (0.80) | TSHRMAPK1MEN1KMT2ATDP1 | |
| S-Ethyl Dipropylcarbamothioate SCHEMBL11347969 | 0.76 | TSHR (0.95) | TSHRMAPK1MEN1KMT2ATDP1 | |
| Molinate SCHEMBL11745944 | 0.73 | TSHR (0.43) | TSHRMAPK1L3MBTL1MEN1KMT2A | |
| S-Ethyl Dipropylcarbamothioate SCHEMBL15019931 | 0.72 | TSHR (0.43) | TSHRMAPK1HRH3NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171356-A | Thiolcarbamate and nonphytotoxic extender which minimizes soil degradation | ICI AMERICAS INC. (US) | 1992-12-15 | — | — | US | disclosed |
| US-4762548-A | HALOALLYL-SUBSTITUTED AMIDE EXTENDER FOR A THIOLCARBAMATE | STAUFFER CHEMICAL CO. (US) | 1988-08-09 | — | — | US | disclosed |