⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9508799 | 0.92 | — | — | |
| SCHEMBL9510318 | 0.92 | — | — | |
| SCHEMBL27501732 | 0.91 | — | — | |
| SCHEMBL9510303 | 0.91 | — | — | |
| SCHEMBL9515683 | 0.90 | — | — | |
| SCHEMBL9652793 | 0.84 | ATP4A (0.53) | — | |
| SCHEMBL10473762 | 0.84 | — | — | |
| SCHEMBL9650915 | 0.82 | — | — | |
| SCHEMBL9725711 | 0.82 | ATP4A (0.63) | — | |
| SCHEMBL9650997 | 0.82 | ATP4A (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143920-A | Antiulcer, antisecretory | SMITHKLINE BECKMAN INTERCREDIT B.V. (NL) | 1992-09-01 | — | — | US | disclosed |
| EP-0342775-A1 | 4-Amino-3-acylquinoline derivatives and their use as inhibitors of gastric secretion | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1989-11-23 | — | — | EP | disclosed |
| CN-1035663-A | The preparation method of the quinoline that replaces | SMITHKLINE BECKMAN INTERCREDIT (NL) | 1989-09-20 | — | — | CN | disclosed |
| WO-1989008105-A1 | 4-AMINO-3-ACYLQUINOLINE DERIVATIVES AND THEIR USE AS INHIBITORS OF GASTRIC SECRETION | SMITHKLINE BECKMAN INTERCREDIT B.V. (NL) | 1989-09-08 | — | — | WO | disclosed |