Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 14/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7288303 | 0.91 | REN (0.47) | RENCTSSCTSL | |
| SCHEMBL7288300 | 0.91 | REN (0.47) | RENCTSSCTSL | |
| SCHEMBL7268094 | 0.84 | REN (0.46) | RENCTSSHDAC1HDAC2CTSL | |
| SCHEMBL7268091 | 0.84 | REN (0.46) | RENCTSSHDAC1HDAC2CTSL | |
| SCHEMBL9725820 | 0.83 | REN (0.49) | RENCTSSCTSL | |
| SCHEMBL9725773 | 0.80 | REN (0.46) | RENCTSSCTSL | |
| SCHEMBL9725744 | 0.79 | REN (0.47) | RENCTSSCTSL | |
| SCHEMBL9725854 | 0.78 | REN (0.47) | RENCTSSCTSL | |
| SCHEMBL9725888 | 0.76 | REN (0.47) | REN | |
| SCHEMBL9725823 | 0.73 | REN (0.47) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106835-A | Hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1992-04-21 | — | — | US | claimed |