SCHEMBL9725846

SCHEMBL9725846

CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@H](CC1CCCCC1)[C@H](O)c1cccs1

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
REN P00797 20/20 0.53
PGC P20142 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9725848 1.00 REN (0.53) RENPGC
SCHEMBL7333289 0.95 REN (0.46) RENPGC
SCHEMBL7333295 0.95 REN (0.46) RENPGC
SCHEMBL7370857 0.90 REN (0.54) RENPGC
SCHEMBL9725801 0.88 REN (0.52) REN
SCHEMBL9725807 0.88 REN (0.52) REN
SCHEMBL7386767 0.88 REN (0.57) RENPGC
SCHEMBL7271925 0.88 REN (0.57) RENPGC
SCHEMBL7269524 0.87 REN (0.52) REN
SCHEMBL7269528 0.87 REN (0.52) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5106835-A Hypotensive agents AMERICAN CYANAMID COMPANY (US) 1992-04-21 US claimed