Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 3/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | FAP | Q12884 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726002 | 1.00 | CACNA1C (0.35) | CACNA1CPTGS1ESR1PDE4AMEN1 | |
| SCHEMBL10516520 | 0.87 | FAAH (0.30) | FAAH | |
| SCHEMBL9726047 | 0.87 | FAAH (0.30) | FAAH | |
| SCHEMBL9726053 | 0.85 | — | — | |
| SCHEMBL9726035 | 0.83 | ESR1 (0.39) | CACNA1CPTGS1ESR1PDE4AMEN1 | |
| SCHEMBL9726106 | 0.82 | KDM4E (0.38) | PTGS1ESR1MEN1KMT2AFAAH | |
| SCHEMBL9726108 | 0.82 | KDM4E (0.38) | PTGS1ESR1MEN1KMT2AFAAH | |
| SCHEMBL10516511 | 0.80 | — | — | |
| SCHEMBL9681789 | 0.76 | FAAH (0.35) | CACNA1CPTGS1ESR1PDE4AMEN1 | |
| SCHEMBL9195919 | 0.75 | ESR1 (0.41) | PTGS1ESR1MEN1KMT2AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081237-A | Chemical intermediates for bactericides | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1992-01-14 | — | — | US | disclosed |
| US-4923857-A | CARBAPENICILLINS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-05-08 | — | — | US | disclosed |
| EP-0330108-A1 | 3-Alkenyl-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-08-30 | — | — | EP | disclosed |