Triaziquone

Triaziquone

SCHEMBL9726159

CC(C)=C(C)C(=O)O.O=C1C=C(N2CC2)C(=O)C(N2CC2)=C1N1CC1

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.37
MAPT P10636 1/20 0.37
STAT3 P40763 1/20 0.37
HTT P42858 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
DNMT1 P26358 1/20 0.36
APAF1 O14727 1/20 0.30
TDP2 O95551 1/20 0.30
NSD2 O96028 1/20 0.30
HKDC1 Q2TB90 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triaziquone SCHEMBL11422311 0.89 MAPT (0.42) TP53MAPTSTAT3HTTSMN1; SMN2
Triaziquone SCHEMBL16419 0.89 MAPT (0.42) TP53MAPTSTAT3HTTSMN1; SMN2
Triaziquone SCHEMBL10414999 0.87 MAPT (0.41) TP53MAPTSTAT3HTTSMN1; SMN2
Triaziquone SCHEMBL2095563 0.86 TP53 (0.38) TP53MAPTSTAT3HTTSMN1; SMN2
Triaziquone SCHEMBL11744970 0.85 MAPT (0.40) TP53MAPTSTAT3HTTSMN1; SMN2
Triaziquone SCHEMBL8507558 0.82 DNMT1 (0.41) TP53MAPTSTAT3HTTSMN1; SMN2
Triaziquone SCHEMBL8585531 0.81 HTT (0.37) TP53MAPTSTAT3HTTSMN1; SMN2
Triaziquone SCHEMBL8303 0.81 DNMT1 (0.48) TP53MAPTSTAT3HTTSMN1; SMN2
Triaziquone SCHEMBL20742268 0.81 MAPT (0.39) TP53MAPTSTAT3HTTSMN1; SMN2
Triaziquone SCHEMBL11583629 0.81 DNMT1 (0.41) TP53MAPTSTAT3HTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5106720-A Hydroxylated polyamide and(or) polyimide binder, photopolymerizable compound and photoinitiator HOECHST CELANESE CORPORATION (US) 1992-04-21 US disclosed