Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 2/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triaziquone SCHEMBL16419 | 0.90 | MAPT (0.42) | TP53MAPTSTAT3HTTSMN1; SMN2 | |
| Triaziquone SCHEMBL11422311 | 0.90 | MAPT (0.42) | TP53MAPTSTAT3HTTSMN1; SMN2 | |
| Triaziquone SCHEMBL10414999 | 0.88 | MAPT (0.41) | TP53MAPTSTAT3HTTSMN1; SMN2 | |
| Triaziquone SCHEMBL11744970 | 0.87 | MAPT (0.40) | TP53MAPTSTAT3HTTSMN1; SMN2 | |
| Triaziquone SCHEMBL9726159 | 0.86 | TP53 (0.37) | TP53MAPTSTAT3HTTSMN1; SMN2 | |
| Triaziquone SCHEMBL1241564 | 0.84 | TP53 (0.36) | TP53MAPTSTAT3HTTSMN1; SMN2 | |
| Triaziquone SCHEMBL7783197 | 0.84 | MAPT (0.46) | TP53MAPTSTAT3HTTSMN1; SMN2 | |
| Triaziquone SCHEMBL8507558 | 0.83 | DNMT1 (0.41) | TP53MAPTSTAT3HTTSMN1; SMN2 | |
| Triaziquone SCHEMBL2063810 | 0.83 | MAPT (0.44) | TP53MAPTSTAT3HTTSMN1; SMN2 | |
| Triaziquone SCHEMBL8585531 | 0.83 | HTT (0.37) | TP53MAPTSTAT3HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240184137-A1 | CONTACT LENSES AND METHODS OF MAKING CONTACT LENSES | UNIV FLORIDA (US) | 2024-06-06 | — | — | US | claimed |
| WO-2022221259-A1 | CONTACT LENSES AND METHODS OF MAKING CONTACT LENSES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2022-10-20 | — | — | WO | claimed |
| US-20200156336-A1 | METHODS AND COMPOSITIONS FOR PIGMENTED HYDROGELS AND CONTACT LENSES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2020-05-21 | — | — | US | claimed |
| EP-1044227-A1 | PARTIALLY POLYMERIZED MIXTURE OF DIETHYLENE GLYCOL (ALLYL CARBONATE) COMPOUNDS | PPG Industries Ohio, Inc. (US) | 2000-10-18 | — | — | EP | claimed |
| WO-1999033887-A1 | PARTIALLY POLYMERIZED MIXTURE OF DIETHYLENE GLYCOL (ALLYL CARBONATE) COMPOUNDS | PPG INDUSTRIES OHIO, INC. (US) | 1999-07-08 | — | — | WO | claimed |
| US-20240184137-A1 | CONTACT LENSES AND METHODS OF MAKING CONTACT LENSES | UNIV FLORIDA (US) | 2024-06-06 | — | — | US | disclosed |
| EP-4360861-A2 | PROCESS OF MAKING AN OPHTALMICAL DEVICE FOR THE SUPPLY OF HYDROPHOBIC COMFORT AGENTS | Alcon Inc. (CH) | 2024-05-01 | — | — | EP | disclosed |
| EP-3373047-B1 | PROCESS OF MAKING AN OPHTALMICAL DEVICE FOR THE SUPPLY OF HYDROPHOBIC COMFORT AGENTS | ALCON INC (CH) | 2024-03-06 | — | — | EP | disclosed |
| US-11905351-B2 | Silicone hydrogel materials | Envision Biomedical LLC (US) | 2024-02-20 | — | — | US | disclosed |
| US-20240026049-A1 | DUAL-PHASE ZWITTERIONIC MONOMERS | Envision Biomedical LLC (US) | 2024-01-25 | — | — | US | disclosed |
| US-11826974-B2 | Methods and compositions for pigmented hydrogels and contact lenses | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2023-11-28 | — | — | US | disclosed |
| WO-2022221259-A1 | CONTACT LENSES AND METHODS OF MAKING CONTACT LENSES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2022-10-20 | — | — | WO | disclosed |
| EP-0683799-A1 | FLUOROSILICONE HYDROGELS | BAUSCH & LOMB INCORPORATED (US) | 1995-11-29 | — | — | EP | disclosed |
| US-5387662-A | For contact lenses; acrylated polysiloxanes | BAUSCH & LOMB INCORPORATED (US) | 1995-02-07 | — | — | US | disclosed |
| WO-1994018253-A1 | FLUOROSILICONE HYDROGELS | BAUSCH & LOMB INCORPORATED (US) | 1994-08-18 | — | — | WO | disclosed |
| US-5321108-A | Improving solubility of unsaturated siloxane monomers in hydrophilic monomer | BAUSCH & LOMB INCORPORATED (US) | 1994-06-14 | — | — | US | disclosed |
| CN-1085844-A | Making contains the method for the hydrogel lens of silicone | BAUSCH & LOMB (US) | 1994-04-27 | — | — | CN | disclosed |
| WO-1989001461-A1 | CO-SINTERABLE METAL-CERAMIC PACKAGES AND MATERIALS THEREFOR | CERAMICS PROCESS SYSTEMS CORPORATION (US) | 1989-02-23 | — | — | WO | disclosed |
| US-4310615-A | PRESSENSITIZED SHEET | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1982-01-12 | — | — | US | disclosed |
| US-4262079-A | THIN, FLEXIBLE, TRANSPARENT SUBSTRATE, RELEASE COATING, PHOTOPOLYMERIZABLE OVERLAYER | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1981-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240026049-A1 | DUAL-PHASE ZWITTERIONIC MONOMERS | RAD1, RAD51, VCL | TP53 2992/4885MAPT 2034/4885STAT3 4594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.