Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | KHK | P50053 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SYK | P43405 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726295 | 0.85 | MAPK1 (0.31) | KDM5BDHODH | |
| SCHEMBL27674658 | 0.82 | KDM4E (0.36) | KDM5BDHODHKDM4EADORA3 | |
| SCHEMBL10566847 | 0.81 | SYK (0.30) | KDM5BSYK | |
| SCHEMBL15566483 | 0.81 | KDM4E (0.33) | KDM5BKDM4E | |
| SCHEMBL27692999 | 0.81 | — | — | |
| SCHEMBL8695146 | 0.80 | DPP4 (0.35) | DHODH | |
| SCHEMBL9726385 | 0.80 | NPSR1 (0.36) | KDM5BKDM4EADORA3RXFP1NPSR1 | |
| SCHEMBL27674748 | 0.80 | DPP4 (0.31) | — | |
| SCHEMBL9726378 | 0.79 | KDM4E (0.48) | KDM4EADORA3NPSR1MAPT | |
| SCHEMBL27674760 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5142055-A | Dehydrofluorinating reduced fluoroalkyl pyridine compound | MONSANTO COMPANY (US) | 1992-08-25 | — | — | US | disclosed |
| EP-0133612-B1 | SUBSTITUTED 2,6-SUBSTITUTED PYRIDINE COMPOUNDS | MONSANTO COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |
| US-4978384-A | HERBICIDES | MONSANTO COMPANY (US) | 1990-12-18 | — | — | US | disclosed |
| US-4692184-A | HERBICIDES | MONSANTO COMPANY (US) | 1987-09-08 | — | — | US | disclosed |
| EP-0133612-A2 | Substituted 2,6-substituted pyridine compounds | MONSANTO COMPANY (US) | 1985-02-27 | — | — | EP | disclosed |