Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726378 | 0.85 | KDM4E (0.48) | NPSR1KDM4EALDH1A1PKMLMNA | |
| SCHEMBL9588052 | 0.83 | LMNA (0.33) | NPC1PKMCNR2LMNA | |
| SCHEMBL9589426 | 0.82 | CNR2 (0.31) | CNR2 | |
| SCHEMBL8692924 | 0.82 | GCGR (0.35) | NPSR1KDM4ETSHRMAPK1ALDH1A1 | |
| SCHEMBL9588019 | 0.80 | NOTUM (0.33) | NPSR1KDM4ETSHRALDH1A1NOTUM | |
| SCHEMBL9591291 | 0.80 | CNR2 (0.32) | CNR2 | |
| SCHEMBL9726384 | 0.80 | KDM5B (0.36) | NPSR1KDM4ERXFP1KDM5BMAPT | |
| SCHEMBL9726386 | 0.75 | LMNA (0.32) | ALDH1A1NPC1PKMLMNAMAPT | |
| SCHEMBL10474021 | 0.75 | KDM4E (0.37) | NPSR1KDM4ETSHRMAPK1ALDH1A1 | |
| SCHEMBL9726358 | 0.75 | KDM4E (0.34) | NPSR1KDM4EALDH1A1NPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5142055-A | Dehydrofluorinating reduced fluoroalkyl pyridine compound | MONSANTO COMPANY (US) | 1992-08-25 | — | — | US | disclosed |
| EP-0133612-B1 | SUBSTITUTED 2,6-SUBSTITUTED PYRIDINE COMPOUNDS | MONSANTO COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |
| US-4978384-A | HERBICIDES | MONSANTO COMPANY (US) | 1990-12-18 | — | — | US | disclosed |
| US-4826530-A | PREEEMERGENCE AND SELECTIVE POSTEMEREGENCE HERBICIDES | MONSANTO COMPANY (US) | 1989-05-02 | — | — | US | disclosed |
| US-4692184-A | HERBICIDES | MONSANTO COMPANY (US) | 1987-09-08 | — | — | US | disclosed |
| EP-0133612-A2 | Substituted 2,6-substituted pyridine compounds | MONSANTO COMPANY (US) | 1985-02-27 | — | — | EP | disclosed |