SCHEMBL9726396

SCHEMBL9726396

COC(=O)c1c(C(F)F)nc(C(F)(F)F)c(C(=O)OC)c1CSC

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GCGR P47871 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9726390 0.93 KDM4E (0.36)
SCHEMBL6738295 0.87 GCGR (0.31) GCGR
SCHEMBL9726392 0.85 GCGR (0.32) GCGR
SCHEMBL8693608 0.84 GCGR (0.34) GCGR
SCHEMBL9589426 0.82 CNR2 (0.31) GCGR
SCHEMBL27257197 0.81
SCHEMBL9591291 0.81 CNR2 (0.32) GCGR
SCHEMBL9588052 0.81 LMNA (0.33) GCGR
SCHEMBL8310160 0.80 GCGR (0.32) GCGR
SCHEMBL9726357 0.79 KDM4E (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5142055-A Dehydrofluorinating reduced fluoroalkyl pyridine compound MONSANTO COMPANY (US) 1992-08-25 US disclosed
EP-0133612-B1 SUBSTITUTED 2,6-SUBSTITUTED PYRIDINE COMPOUNDS MONSANTO COMPANY (US) 1991-02-27 EP disclosed
US-4978384-A HERBICIDES MONSANTO COMPANY (US) 1990-12-18 US disclosed
US-4826530-A PREEEMERGENCE AND SELECTIVE POSTEMEREGENCE HERBICIDES MONSANTO COMPANY (US) 1989-05-02 US disclosed
US-4692184-A HERBICIDES MONSANTO COMPANY (US) 1987-09-08 US disclosed
EP-0133612-A2 Substituted 2,6-substituted pyridine compounds MONSANTO COMPANY (US) 1985-02-27 EP disclosed