Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.53 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.51 |
| ▸ | NAMPT | P43490 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5731734 | 0.85 | LOXL2 (0.49) | HDAC3HDAC6NCOR2LOXL2NAMPT | |
| Hydrochloric Acid SCHEMBL5846568 | 0.84 | LOXL2 (0.47) | HDAC3HDAC6NCOR2LOXL2NAMPT | |
| SCHEMBL23254739 | 0.84 | MCHR1 (0.49) | HDAC3HDAC6NCOR2LOXL2NAMPT | |
| SCHEMBL13009920 | 0.84 | HDAC6 (0.49) | HDAC3HDAC6NCOR2LOXL2NAMPT | |
| SCHEMBL1435144 | 0.83 | HDAC1 (0.54) | HDAC3HDAC6NCOR2LOXL2NAMPT | |
| SCHEMBL15588634 | 0.82 | MEN1 (0.46) | NAMPTHDAC1 | |
| SCHEMBL18226968 | 0.81 | CA1 (0.48) | HDAC3HDAC6NCOR2LOXL2NAMPT | |
| SCHEMBL16168333 | 0.81 | HDAC3 (0.50) | HDAC3HDAC6NCOR2LOXL2NAMPT | |
| SCHEMBL4749029 | 0.80 | MAPT (0.55) | NAMPTCA12CA1CA7CA14 | |
| SCHEMBL21584892 | 0.80 | EPHX1 (0.54) | HDAC3HDAC6NCOR2HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098900-A | Reducing contractions in smooth muscles | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-03-24 | — | — | US | disclosed |