Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 10/20 | 0.52 |
| ▸ | CDC25B | P30305 | 8/20 | 0.52 |
| ▸ | PTPN2 | P17706 | 6/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.49 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.49 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.48 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.48 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.48 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.48 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.48 |
| ▸ | NT5E | P21589 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | GJB2 | P29033 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727010 | 1.00 | PTPN1 (0.52) | PTPN1CDC25BPTPN2PTPN11PTPN6 | |
| SCHEMBL4761028 | 0.92 | SSTR1 (0.55) | PTPN1CDC25BPTPN2PTPN11PTPN6 | |
| SCHEMBL4761024 | 0.92 | SSTR1 (0.55) | PTPN1CDC25BPTPN2PTPN11PTPN6 | |
| SCHEMBL9727220 | 0.92 | PTPN1 (0.47) | PTPN1CDC25BPTPN2PTPN11PTPN6 | |
| SCHEMBL9727225 | 0.92 | PTPN1 (0.47) | PTPN1CDC25BPTPN2PTPN11PTPN6 | |
| SCHEMBL8992144 | 0.90 | SSTR1 (0.60) | PTPN1CDC25BPTPN2PTPN11PTPN6 | |
| SCHEMBL8992149 | 0.90 | SSTR1 (0.60) | PTPN1CDC25BPTPN2PTPN11PTPN6 | |
| SCHEMBL8992053 | 0.90 | PDE4D (0.46) | PTPN1CDC25BPTPN2PTPN11PTPN6 | |
| SCHEMBL8992043 | 0.90 | PDE4D (0.46) | PTPN1CDC25BPTPN2PTPN11PTPN6 | |
| SCHEMBL9727120 | 0.88 | SSTR1 (0.51) | PTPN1CDC25BPTPN2PTPN11PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5157116-A | Antidiabetic agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-10-20 | — | — | US | disclosed |