Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.42 |
| ▸ | CDC25B | P30305 | 5/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | GJB2 | P29033 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | TACR2 | P21452 | 2/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8992043 | 1.00 | PDE4D (0.46) | PDE4DSLC6A2PTPN1CDC25BHTR1A | |
| SCHEMBL9727220 | 0.90 | PTPN1 (0.47) | SLC6A2PTPN1CDC25BNT5EGJB2 | |
| SCHEMBL9727010 | 0.90 | PTPN1 (0.52) | PTPN1CDC25BHTR1ANT5EGJB2 | |
| SCHEMBL9727015 | 0.90 | PTPN1 (0.52) | PTPN1CDC25BHTR1ANT5EGJB2 | |
| SCHEMBL9727225 | 0.90 | PTPN1 (0.47) | SLC6A2PTPN1CDC25BNT5EGJB2 | |
| SCHEMBL1562065 | 0.88 | HTR1A (0.52) | PDE4DPTPN1CDC25BHTR1ANT5E | |
| SCHEMBL14747295 | 0.88 | HTR1A (0.52) | PDE4DPTPN1CDC25BHTR1ANT5E | |
| SCHEMBL264552 | 0.88 | HTR1A (0.52) | PDE4DPTPN1CDC25BHTR1ANT5E | |
| SCHEMBL5027926 | 0.88 | HTR1A (0.52) | PDE4DPTPN1CDC25BHTR1ANT5E | |
| SCHEMBL12896357 | 0.88 | HTR1A (0.52) | PDE4DPTPN1CDC25BHTR1ANT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5504078-A | α-glucosidase inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1996-04-02 | — | — | US | disclosed |
| EP-0532668-B1 | NOVEL ALPHA-GLUCOSIDASE INHIBITORS | MERRELL DOW PHARMA (US) | 1995-11-15 | — | — | EP | disclosed |
| EP-0345104-B1 | Novel Alpha-glucosidase inhibitors | MERRELL DOW PHARMA (US) | 1995-11-02 | — | — | EP | disclosed |
| EP-0422975-B1 | Alpha-glucosidase inhibitors | MERRELL DOW PHARMA (US) | 1994-07-27 | — | — | EP | disclosed |
| US-5157116-A | Antidiabetic agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-10-20 | — | — | US | disclosed |
| US-5097023-A | α-glucosidase inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-03-17 | — | — | US | disclosed |