Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GJB2 | P29033 | 3/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.48 |
| ▸ | NT5E | P21589 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.46 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.46 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.46 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.46 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 6/20 | 0.45 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.45 |
| ▸ | GJA1 | P17302 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727044 | 1.00 | GJB2 (0.51) | GJB2PTPN1PTPN2PTPN11NT5E | |
| SCHEMBL1776650 | 0.94 | PTPN1 (0.52) | GJB2PTPN1PTPN2PTPN11NT5E | |
| SCHEMBL1776647 | 0.94 | PTPN1 (0.52) | GJB2PTPN1PTPN2PTPN11NT5E | |
| SCHEMBL9727114 | 0.91 | SSTR1 (0.51) | GJB2PTPN1PTPN2PTPN11NT5E | |
| SCHEMBL9727120 | 0.91 | SSTR1 (0.51) | GJB2PTPN1PTPN2PTPN11NT5E | |
| SCHEMBL10607794 | 0.90 | SSTR1 (0.58) | GJB2PTPN1PTPN2PTPN11NT5E | |
| SCHEMBL8992046 | 0.90 | SSTR1 (0.58) | GJB2PTPN1PTPN2PTPN11NT5E | |
| SCHEMBL8992050 | 0.90 | SSTR1 (0.58) | GJB2PTPN1PTPN2PTPN11NT5E | |
| SCHEMBL7753913 | 0.89 | SLC6A2 (0.52) | GJB2PTPN1PTPN2PTPN11NT5E | |
| SCHEMBL22710060 | 0.89 | GJB2 (0.46) | GJB2PTPN1NT5ESLC6A2SSTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5157116-A | Antidiabetic agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-10-20 | — | — | US | disclosed |