SCHEMBL9727085

SCHEMBL9727085

O=C(O)NN1CCCCCC1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.52
ALDH1A1 P00352 3/20 0.42
KDM4E B2RXH2 1/20 0.42
TP53 P04637 1/20 0.42
GLA P06280 1/20 0.42
CYP3A4 P08684 1/20 0.42
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
ALOX12 P18054 1/20 0.42
NFKB1 P19838 1/20 0.42
LIPE Q05469 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
LMNA P02545 1/20 0.39
POLB P06746 1/20 0.39
CYP1A2 P05177 1/20 0.38
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CNR1 P21554 4/20 0.37
CNR2 P34972 2/20 0.36
EPHX2 P34913 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34638 1.00 HTT (0.52) HTTALDH1A1KDM4ETP53GLA
Hydrochloric Acid SCHEMBL8939931 0.97 HTT (0.50) HTTALDH1A1KDM4ETP53GLA
SCHEMBL477228 0.97
Benzene SCHEMBL8030551 0.95 HTT (0.59) HTTALDH1A1KDM4ETP53GLA
Hydrochloric Acid SCHEMBL11600093 0.94 HTT (0.47) HTTALDH1A1KDM4ETP53GLA
Benzene SCHEMBL3841909 0.92 HTT (0.55) HTTALDH1A1KDM4ETP53GLA
SCHEMBL1801925 0.92
SCHEMBL10879021 0.89 HTT (0.44) HTTALDH1A1KDM4ETP53GLA
SCHEMBL18124344 0.89 HTT (0.44) HTTALDH1A1KDM4ETP53GLA
Piperidine SCHEMBL25200840 0.87 HTT (0.43) HTTALDH1A1KDM4ETP53GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101817815-A Compounds with antibacterial activity MORPHOCHEM AG KOMB CHEMIE 2010-09-01 CN disclosed
CN-100569769-C Compounds with fungicidal activity MORPHOCHEM AG KOMB CHEMIE (DE) 2009-12-16 CN disclosed
CN-1703412-A Novel compounds with fungicidal activity MORPHOCHEM AG KOMB CHEMIE (DE) 2005-11-30 CN disclosed
US-5162528-A Pre- and post-emergence; phytaphthora in tomato plants; rice and wheat BAYER AKTIENGESELLSCHAFT (DE) 1992-11-10 US disclosed
US-5028717-A Herbicidal and fungicidal agents based on substituted pyrazolin-5-one derivatives BAYER AKTIENGESELLSCHAFT (DE) 1991-07-02 US disclosed
US-4909827-A Containing a C6-10 aryl group substituted in position 1 BAYER AKTIENGESELLSCHAFT (DE) 1990-03-20 US disclosed