Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | NOS3 | P29474 | 1/20 | 0.51 |
| ▸ | NOS2 | P35228 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.45 |
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16023879 | 0.84 | RAB9A (0.56) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL28748513 | 0.84 | SCN9A (0.48) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL5646966 | 0.84 | NPC1 (0.56) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL9338840 | 0.84 | NPC1 (0.56) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL15272369 | 0.84 | NPC1 (0.60) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL31411241 | 0.83 | NPC1 (0.56) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL19154982 | 0.83 | NPC1 (0.56) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL30334561 | 0.83 | MAPK1 (0.50) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL9223761 | 0.83 | MAPK1 (0.50) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL21630346 | 0.81 | NPC1 (0.54) | RAB9ANPC1CASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132314-A | For administration to mammals, anthranilic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1992-07-21 | — | — | US | claimed |
| US-5132314-A | For administration to mammals, anthranilic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1992-07-21 | — | — | US | disclosed |
| US-5081125-A | Substituted anthranilic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1992-01-14 | — | — | US | disclosed |