Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 7/20 | 0.59 |
| ▸ | MMP13 | P45452 | 6/20 | 0.59 |
| ▸ | MMP3 | P08254 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MMP1 | P03956 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | AIMP2 | Q13155 | 2/20 | 0.50 |
| ▸ | MMP12 | P39900 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22500602 | 0.78 | MAPT (0.59) | MAPTPOLBMEN1KMT2AAIMP2 | |
| SCHEMBL22500385 | 0.77 | AIMP2 (0.64) | MAPTPOLBMEN1KMT2AAIMP2 | |
| SCHEMBL22500500 | 0.77 | AIMP2 (0.64) | MAPTPOLBMEN1KMT2AAIMP2 | |
| SCHEMBL3427026 | 0.77 | TDP1 (0.64) | MMP2MMP13MMP3MMP1 | |
| SCHEMBL3392197 | 0.77 | TDP1 (0.64) | MMP2MMP13MMP3MMP1 | |
| SCHEMBL3397101 | 0.77 | TDP1 (0.64) | MMP2MMP13MMP3MMP1 | |
| SCHEMBL10076154 | 0.76 | MMP2 (0.59) | MMP2MMP13MAPTMMP12 | |
| SCHEMBL10687687 | 0.76 | MMP2 (0.59) | MMP2MMP13MAPTMMP12 | |
| SCHEMBL22500268 | 0.76 | AIMP2 (0.66) | MAPTPOLBMEN1KMT2AAIMP2 | |
| SCHEMBL22500619 | 0.76 | AIMP2 (0.66) | MAPTPOLBMEN1KMT2AAIMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5164514-A | Antispasmodics | ROUSSEL UCLAF (FR) | 1992-11-17 | — | — | US | disclosed |
| US-5081130-A | Antispasmodic agents | ROUSSEL UCLAF (FR) | 1992-01-14 | — | — | US | disclosed |
| US-4990531-A | Antispasmodic agents | ROUSSEL UCLAF (FR) | 1991-02-05 | — | — | US | disclosed |