Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 14/20 | 0.72 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1809116 | 0.84 | APP (1.00) | APPPRMT1 | |
| Hydrochloric Acid SCHEMBL1809114 | 0.84 | APP (1.00) | APPPRMT1 | |
| SCHEMBL1805580 | 0.81 | APP (1.00) | APP | |
| SCHEMBL1805582 | 0.81 | APP (1.00) | APP | |
| Hydrochloric Acid SCHEMBL1806347 | 0.80 | APP (1.00) | APPPRMT1 | |
| Hydrochloric Acid SCHEMBL1806350 | 0.80 | APP (1.00) | APPPRMT1 | |
| SCHEMBL9727779 | 0.79 | APP (0.75) | APPMAOAMAOBKDM4EMAPT | |
| SCHEMBL31709160 | 0.79 | APP (0.64) | APPPRMT1MAPT | |
| SCHEMBL1809144 | 0.79 | APP (0.68) | APPPRMT1MAOAMAOBKDM4E | |
| SCHEMBL1809143 | 0.79 | APP (0.68) | APPPRMT1MAOAMAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091533-A | Treating allergies, cardiovascular disorders, inflammation | MERCK FROSST CANADA, INC. (CA) | 1992-02-25 | — | — | US | disclosed |
| EP-0447189-A1 | 5-Hydroxy-2,3-dihydrobenzofuran analogs as leukotriene biosynthesis inhibitors | MERCK FROSST CANADA INC. (CA) | 1991-09-18 | — | — | EP | disclosed |