Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GCK | P35557 | 1/20 | 0.44 |
| ▸ | GCKR | Q14397 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6176528 | 0.89 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2KDM4EPOLBRAB9A | |
| SCHEMBL6176174 | 0.87 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2KDM4EPOLBRAB9A | |
| SCHEMBL10757128 | 0.87 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2KDM4EPOLBRAB9A | |
| SCHEMBL8006677 | 0.87 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2KDM4EPOLBRAB9A | |
| SCHEMBL11558383 | 0.86 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2KDM4EPOLBRAB9A | |
| SCHEMBL6173806 | 0.84 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2KDM4EPOLBRAB9A | |
| SCHEMBL2149591 | 0.83 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2KDM4EPOLBRAB9A | |
| SCHEMBL10963741 | 0.82 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2KDM4EPOLBRAB9A | |
| SCHEMBL6977861 | 0.81 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2KDM4EPOLBRAB9A | |
| SCHEMBL10376457 | 0.81 | CYP3A4 (0.50) | ALDH1A1SMN1; SMN2KDM4EPOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132314-A | For administration to mammals, anthranilic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1992-07-21 | — | — | US | disclosed |
| US-5081125-A | Substituted anthranilic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1992-01-14 | — | — | US | disclosed |
| EP-0420804-A2 | Anthelmintic compounds | CIBA-GEIGY AG (CH) | 1991-04-03 | — | — | EP | disclosed |
| US-4173637-A | N-Benzoyl-N'-pyridyloxy phenyl urea and insecticidal compositions thereof | ISHIHARA SANGYO KAISHA LTD. (JP) | 1979-11-06 | — | — | US | disclosed |