Benzonitrile

Benzonitrile

SCHEMBL9727712

CC(C)C#N.N#Cc1ccccc1

nearest known ligand 0.70

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Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.70
MAOB P27338 4/20 0.46
MAOA P21397 3/20 0.46
CYP2A6 P11509 2/20 0.44
ALDH1A1 P00352 1/20 0.44
HDAC8 Q9BY41 2/20 0.41
TRPA1 O75762 1/20 0.39
APP P05067 1/20 0.39
CA12 O43570 1/20 0.39
CA2 P00918 1/20 0.39
CA3 P07451 1/20 0.39
CA6 P23280 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39
OPRD1 P41143 1/20 0.38
GLA P06280 1/20 0.38
HTR2A P28223 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzonitrile SCHEMBL29115799 0.93 TSHR (0.61) TSHRMAOBMAOACYP2A6ALDH1A1
Benzonitrile SCHEMBL28306408 0.85 TSHR (0.70) TSHRMAOBMAOACYP2A6ALDH1A1
Benzonitrile SCHEMBL11563021 0.85 TSHR (0.70) TSHRMAOBMAOACYP2A6ALDH1A1
Benzonitrile SCHEMBL27895262 0.84 TSHR (0.88) TSHRMAOBMAOACYP2A6ALDH1A1
Benzonitrile SCHEMBL2154015 0.84 TSHR (0.88) TSHRMAOBMAOACYP2A6ALDH1A1
Benzonitrile SCHEMBL6640 0.84
Benzonitrile SCHEMBL11044747 0.84
Benzonitrile SCHEMBL9464940 0.84 TSHR (1.00) TSHRMAOBMAOACYP2A6ALDH1A1
Benzonitrile SCHEMBL30929383 0.84 TSHR (1.00) TSHRMAOBMAOACYP2A6ALDH1A1
Benzonitrile SCHEMBL21752925 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108047369-A A kind of holography optical storage polymer and its manufacturing method 电子科技大学 2018-05-18 CN claimed
CN-110054732-A Surface coating polymerization object, preparation method and application 中山大学 2019-07-26 CN disclosed
US-5163992-A OXALIC ACID DERIVATIVES AND PLANT GROWTH REGULATORS CONTAINING THEM BASF AKTIENGESELLSCHAFT (DE) 1992-11-17 US disclosed