Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.39 |
| ▸ | WNT3A | P56704 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TTK | P33981 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2268137 | 1.00 | KDM4E (0.44) | KDM4EGAAPDPK1CYP3A4STAT3 | |
| SCHEMBL2268086 | 1.00 | KDM4E (0.44) | KDM4EGAAPDPK1CYP3A4STAT3 | |
| SCHEMBL30166149 | 0.79 | SLC6A2 (0.50) | KDM4EGAAPDPK1CYP3A4STAT3 | |
| SCHEMBL5989957 | 0.79 | SLC6A2 (0.50) | KDM4EGAAPDPK1CYP3A4STAT3 | |
| SCHEMBL2268091 | 0.78 | KDM4E (0.44) | KDM4EGAAPDPK1CYP3A4STAT3 | |
| SCHEMBL2268143 | 0.78 | KDM4E (0.44) | KDM4EGAAPDPK1CYP3A4STAT3 | |
| SCHEMBL31642427 | 0.77 | KDM4E (0.55) | KDM4EGAAPDPK1CYP3A4STAT3 | |
| SCHEMBL7416939 | 0.77 | KDM4E (0.55) | KDM4EGAAPDPK1CYP3A4STAT3 | |
| SCHEMBL29353985 | 0.77 | KDM4E (0.55) | KDM4EGAAPDPK1CYP3A4STAT3 | |
| SCHEMBL31646447 | 0.77 | KDM4E (0.55) | KDM4EGAAPDPK1CYP3A4STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417454-A2 | Reduced size LHRH analogs | ABBOTT LABORATORIES (US) | 1991-03-20 | — | — | EP | claimed |
| US-5140009-A | Stable against proteolytic enzymes; anticarcinogenic agents; urogenital disorders | TAP PHARMACEUTICALS, INC. (US) | 1992-08-18 | — | — | US | disclosed |
| EP-0417454-A2 | Reduced size LHRH analogs | ABBOTT LABORATORIES (US) | 1991-03-20 | — | — | EP | disclosed |