Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMUR2 | Q9GZQ4 | 5/20 | 0.53 |
| ▸ | NMUR1 | Q9HB89 | 5/20 | 0.53 |
| ▸ | EPHA2 | P29317 | 4/20 | 0.51 |
| ▸ | RAMP3 | O60896 | 1/20 | 0.50 |
| ▸ | CALCR | P30988 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10586963 | 0.85 | NMUR2 (0.57) | NMUR2NMUR1EPHA2OPRM1OPRK1 | |
| SCHEMBL29390426 | 0.83 | OPRM1 (0.61) | NMUR2NMUR1EPHA2RAMP3CALCR | |
| SCHEMBL31307275 | 0.83 | RAMP3 (0.62) | NMUR2NMUR1EPHA2RAMP3CALCR | |
| SCHEMBL9852755 | 0.83 | NMUR2 (0.47) | NMUR2NMUR1EPHA2KDM1ANTSR2 | |
| SCHEMBL9852750 | 0.82 | NPY4R (0.58) | NMUR2NMUR1EPHA2OPRM1OPRD1 | |
| SCHEMBL30293724 | 0.82 | NPY4R (0.56) | NMUR2NMUR1EPHA2OPRM1 | |
| SCHEMBL30634740 | 0.81 | NMUR2 (0.65) | NMUR2NMUR1EPHA2NTSR2NTSR1 | |
| SCHEMBL10588690 | 0.80 | NPY4R (0.61) | NMUR2NMUR1 | |
| SCHEMBL9632015 | 0.79 | EPHA2 (0.56) | NMUR2NMUR1EPHA2KDM1AOPRM1 | |
| SCHEMBL30680640 | 0.79 | NMUR2 (0.61) | NMUR2NMUR1EPHA2RAMP3CALCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5140009-A | Stable against proteolytic enzymes; anticarcinogenic agents; urogenital disorders | TAP PHARMACEUTICALS, INC. (US) | 1992-08-18 | — | — | US | disclosed |
| EP-0328089-A2 | Reduced size LHRH analogs | ABBOTT LABORATORIES (US) | 1989-08-16 | — | — | EP | disclosed |