Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | IL2 | P60568 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | PPIA | P62937 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728428 | 0.90 | KMT2A (0.61) | KMT2AMEN1USP2MAPTALOX15 | |
| SCHEMBL9728328 | 0.89 | MEN1 (0.49) | KMT2AMEN1USP2MAPTALOX15 | |
| SCHEMBL9728577 | 0.88 | MEN1 (0.54) | KMT2AMEN1USP2MAPTALOX15 | |
| SCHEMBL9728416 | 0.88 | KMT2A (0.59) | KMT2AMEN1USP2MAPTALOX15 | |
| SCHEMBL8011755 | 0.87 | MEN1 (0.57) | KMT2AMEN1USP2MAPTALOX15 | |
| SCHEMBL10848987 | 0.87 | KMT2A (0.73) | KMT2AMEN1USP2MAPTALOX15 | |
| SCHEMBL8014447 | 0.85 | MEN1 (0.60) | KMT2AMEN1USP2MAPTALOX15 | |
| SCHEMBL10347947 | 0.83 | KMT2A (0.67) | KMT2AMEN1USP2MAPTALOX15 | |
| SCHEMBL10615932 | 0.82 | MEN1 (0.51) | KMT2AMEN1USP2MAPTALOX15 | |
| SCHEMBL11619037 | 0.82 | KDR (0.66) | KMT2AMEN1MAPTIL2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0246061-B1 | A BENZOYLUREA DERIVATIVE AND ITS PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-03-18 | — | — | EP | disclosed |