Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PYGL | P06737 | 5/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728667 | 0.90 | KMT2A (0.47) | MEN1KMT2AALOX15USP2MAPT | |
| SCHEMBL9728249 | 0.89 | KMT2A (0.64) | MEN1KMT2AALOX15USP2MAPT | |
| SCHEMBL9727936 | 0.88 | KMT2A (0.40) | MEN1KMT2AALOX15USP2MAPT | |
| SCHEMBL9728939 | 0.88 | KMT2A (0.46) | MEN1KMT2AALOX15USP2MAPT | |
| SCHEMBL10348390 | 0.82 | KMT2A (0.51) | MEN1KMT2AALOX15USP2MAPT | |
| SCHEMBL9743981 | 0.80 | MEN1 (0.43) | MEN1KMT2AALOX15USP2MAPT | |
| SCHEMBL9728428 | 0.79 | KMT2A (0.61) | MEN1KMT2AALOX15USP2MAPT | |
| SCHEMBL9728568 | 0.79 | KMT2A (0.38) | MEN1KMT2AALOX15USP2MAPT | |
| SCHEMBL9728416 | 0.77 | KMT2A (0.59) | MEN1KMT2AALOX15USP2MAPT | |
| SCHEMBL9729612 | 0.76 | KIF11 (0.46) | MEN1KMT2ANPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0246061-B1 | A BENZOYLUREA DERIVATIVE AND ITS PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-03-18 | — | — | EP | disclosed |