SCHEMBL9728304

Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@@H](C(=O)NCC(=O)N[C@@H](Cc1ccc(F)cc1)C(=O)N[C@@H](C(=O)O)C(C)(C)S)C(C)(C)S

nearest known ligand 0.66

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	OPRM1	P35372	10/20	0.66

▸	OPRD1	P41143	9/20	0.48

▸	OPRK1	P41145	6/20	0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9728266	0.93	OPRM1 (0.57)	OPRM1OPRD1OPRK1
SCHEMBL9727846	0.93	OPRM1 (0.76)	OPRM1OPRD1OPRK1
SCHEMBL9728049	0.93	OPRM1 (0.76)	OPRM1OPRD1OPRK1
SCHEMBL9728154	0.92	OPRM1 (0.66)	OPRM1OPRD1OPRK1
SCHEMBL9728033	0.92	OPRM1 (0.66)	OPRM1OPRD1OPRK1
SCHEMBL9497153	0.89	OPRM1 (0.51)	OPRM1OPRK1
SCHEMBL9728127	0.87	OPRM1 (0.70)	OPRM1OPRD1OPRK1
SCHEMBL9728287	0.87	OPRM1 (0.68)	OPRM1OPRD1OPRK1
SCHEMBL9728306	0.86	OPRM1 (0.67)	OPRM1OPRD1OPRK1
SCHEMBL9728212	0.86	OPRM1 (0.58)	OPRM1OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5169833-A	Analgesics	G. D. SEARLE & CO. (US)	1992-12-08	—	—	US	disclosed