⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethyl Methylphosphonate SCHEMBL30393703 | 0.96 | CA2 (0.36) | — | |
| Dimethyl Methylphosphonate SCHEMBL35767 | 0.96 | — | — | |
| Dimethyl Methylphosphonate SCHEMBL27978303 | 0.92 | — | — | |
| Dimethyl Methylphosphonate SCHEMBL626094 | 0.92 | — | — | |
| Dimethyl Methylphosphonate SCHEMBL28200426 | 0.92 | — | — | |
| Dimethyl Methylphosphonate SCHEMBL30950306 | 0.92 | — | — | |
| Dimethyl Methylphosphonate SCHEMBL27738075 | 0.92 | — | — | |
| Dimethyl Methylphosphonate SCHEMBL27763775 | 0.92 | — | — | |
| Dimethyl Methylphosphonate SCHEMBL28197288 | 0.88 | — | — | |
| Dimethyl Methylphosphonate SCHEMBL28016793 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12091432-B2 | Compounds and methods for synthesizing sphingosines and glycolipids | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2024-09-17 | — | — | US | disclosed |
| CN-107973809-B | Macrocyclic compounds as factor XIA inhibitors | 百时美施贵宝公司 | 2023-06-30 | — | — | CN | disclosed |
| US-20220275016-A1 | COMPOUNDS AND METHODS FOR SYNTHESIZING SPHINGOSINES AND GLYCOLIPIDS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION | 2022-09-01 | — | — | US | disclosed |
| US-10640481-B2 | Methods for producing Beraprost and its derivatives | LUNG BIOTECHNOLOGY PBC (US) | 2020-05-05 | — | — | US | disclosed |
| US-20190345190-A1 | PHOSPHONATE ANALOGS OF HIV INHIBITOR COMPOUNDS | GILEAD SCIENCES, INC. | 2019-11-14 | — | — | US | disclosed |
| US-20190315785-A1 | PHOSPHONATE ANALOGS OF HIV INHIBITOR COMPOUNDS | GILEAD SCIENCES, INC. | 2019-10-17 | — | — | US | disclosed |
| EP-3539546-A1 | PHOSPHONATE ANALOGS OF HIV INHIBITOR COMPOUNDS | Gilead Sciences, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| US-20190202797-A1 | METHODS FOR PRODUCING BERAPROST AND ITS DERIVATIVES | LUNG BIOTECHNOLOGY PBC (US) | 2019-07-04 | — | — | US | disclosed |
| US-10246430-B2 | Methods for producing Beraprost and its derivatives | LUNG BIOTECHNOLOGY PBC (US) | 2019-04-02 | — | — | US | disclosed |
| US-20180265490-A1 | METHODS FOR PRODUCING BERAPROST AND ITS DERIVATIVES | LUNG BIOTECHNOLOGY PBC (US) | 2018-09-20 | — | — | US | disclosed |
| US-4410720-A | HYPOTENSIVE AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1983-10-18 | — | — | US | disclosed |
| US-4246426-A | USEFUL IN INDUCING LABOR, TERMINATING PREGNANCY, TREATING GASTRIC HYPERACIDITY, WITH CARDIOVASCULAR AND BRONCHODILATOR EFFECTS | HOFFMANN-LA ROCHE INC. (US) | 1981-01-20 | — | — | US | disclosed |
| US-4246402-A | CARDIOVASCULAR AGENTS AND OXYTOCICS | HOFFMANN-LA ROCHE INC. (US) | 1981-01-20 | — | — | US | disclosed |
| US-4227019-A | CARDIOTONIC AGENTS; OXYTOCICS | HOFFMANN-LA ROCHE INC. (US) | 1980-10-07 | — | — | US | disclosed |
| US-4226985-A | CARDIOVASCULAR AGENTS, OXYTOCICS | HOFFMANN-LA ROCHE INC. (US) | 1980-10-07 | — | — | US | disclosed |
| US-4178461-A | BRONCHODILATORS, GASTRIC ACID SECRETION INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1979-12-11 | — | — | US | disclosed |
| US-4059576-A | CARDIOVASCULAR, OXYTOCICS | HOFFMANN-LA ROCHE, INC. (US) | 1977-11-22 | — | — | US | disclosed |
| US-4052446-A | OXYTOCICS, CARDIOVASCULAR AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1977-10-04 | — | — | US | disclosed |
| US-4036871-A | CARDIOVASCULAR AGENTS, LABOR INDUCERS, ABORTION | HOFFMANN-LA ROCHE INC. (US) | 1977-07-19 | — | — | US | disclosed |
| US-4028396-A | BRONCHODILATORS, GASTRIC ACID SECRETION INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1977-06-07 | — | — | US | disclosed |