Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 6/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9728714 | 0.84 | CHRM2 (0.37) | CHRM4CHRM2CHRM5CHRM3 | |
| SCHEMBL9728601 | 0.78 | CHRM1 (0.41) | CHRM1CHRM4CHRM2CHRM5CHRM3 | |
| SCHEMBL9728317 | 0.76 | CHRM1 (0.55) | CHRM1CHRM4CHRM2CHRM5CHRM3 | |
| SCHEMBL10433205 | 0.73 | CHRM1 (0.49) | CHRM1CHRM4CHRM2CHRM5CHRM3 | |
| Fumaric Acid SCHEMBL195353 | 0.72 | CHRM1 (0.45) | CHRM1CHRM4CHRM2CHRM5CHRM3 | |
| Hydrochloric Acid SCHEMBL9728050 | 0.72 | CHRM1 (0.50) | CHRM1CHRM4CHRM2CHRM5CHRM3 | |
| SCHEMBL9729003 | 0.69 | CHRM2 (0.40) | CHRM1CHRM4CHRM2CHRM5CHRM3 | |
| SCHEMBL9728928 | 0.68 | CHRM1 (0.59) | CHRM1CHRM4CHRM2CHRM5CHRM3 | |
| SCHEMBL9728143 | 0.67 | CHRM2 (0.38) | CHRM1CHRM4CHRM2CHRM5CHRM3 | |
| SCHEMBL7612125 | 0.65 | CHRM1 (1.00) | CHRM1CHRM4CHRM2CHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2180881-A | — | — | None | — | — | JP | disclosed |
| US-5128340-A | Thiazole derivatives | AKZO N.V. (NL) | 1992-07-07 | — | — | US | disclosed |
| JP-H02180881-A | THIAZOLE DERIVATIVE | AKZO NV | 1990-07-13 | — | — | JP | disclosed |
| EP-0372125-A1 | Oxazole and thiazole derivatives | AKZO N.V. (NL) | 1990-06-13 | — | — | EP | disclosed |
| EP-0368384-A1 | Thiazole derivatives | AKZO N.V. (NL) | 1990-05-16 | — | — | EP | disclosed |