Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 10/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL195353 | 0.89 | CHRM1 (0.45) | CHRM1CHRM4CHRM2CHRM5CHRM3 | |
| SCHEMBL9728716 | 0.82 | CHRM2 (0.41) | CHRM4CHRM2CHRM5CHRM3 | |
| SCHEMBL9728112 | 0.82 | RAD52 (0.43) | — | |
| SCHEMBL10433205 | 0.80 | CHRM1 (0.49) | CHRM1CHRM4CHRM2CHRM5CHRM3 | |
| SCHEMBL9728399 | 0.79 | CHRM1 (0.35) | CHRM1 | |
| Hydrochloric Acid SCHEMBL9729647 | 0.78 | CHRM1 (0.44) | CHRM1CHRM4CHRM2CHRM5CHRM3 | |
| Hydrochloric Acid SCHEMBL9728050 | 0.78 | CHRM1 (0.50) | CHRM1CHRM4CHRM2CHRM5CHRM3 | |
| SCHEMBL9727860 | 0.77 | SIGMAR1 (0.41) | — | |
| SCHEMBL9728521 | 0.76 | MAPT (0.41) | — | |
| SCHEMBL9728496 | 0.76 | CHRM1 (0.48) | CHRM1CHRM4CHRM2CHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128340-A | Thiazole derivatives | AKZO N.V. (NL) | 1992-07-07 | — | — | US | disclosed |
| EP-0372125-A1 | Oxazole and thiazole derivatives | AKZO N.V. (NL) | 1990-06-13 | — | — | EP | disclosed |
| EP-0368384-A1 | Thiazole derivatives | AKZO N.V. (NL) | 1990-05-16 | — | — | EP | disclosed |